Margaret Kidwell
Regents Professor Emerita
Positions and Education:
- B. Sc., Nottingham University, UK. 1953
- M.S., Iowa State University, 1962
- Ph.D., Brown University, 1973
- 1955-60 Officer in the National Agricultural Advisory Service, London, England
- 1960-61 Kellogg Foundation Fellow, Iowa State University
- 1966-70 Associate in Research, Brown University
- 1971-72 Teaching Assistant, Brown University
- 1973-74 Research Fellow, Brown University
- 1974-75 Research Associate, Brown University
- 1975-77 Investigator, Brown University
- 1977-80 Assistant Professor (Research), Brown University
- 1978 Visiting Scholar, Institute of Animal Genetics, Edinburgh
- 1980-84 Associate Professor of Biology (Research), Brown University
- 1981 Visiting Distinguished Lecturer at the University of Texas at Austin
- 1984-85 Professor of Biology, Brown University
- 1984 Visiting Scholar, Dept. of Genetics, Cambridge University, England and Dept. of Biochemistry, Imperial College, London
- 1985-94 Professor of Ecology and Evolutionary Biology, University of Arizona
- 1988-91 Chair, Interdisciplinary Program in Genetics, University of Arizona.
- 1991-92 Sabbatical leave, University of Edinburgh, Scotland.
- 1992-97 Head, Dept. of Ecology and Evolutionary Biology, University of Arizona.
- 1994-01 Regents' Professor of Ecology and Evolutionary Biology, University of Arizona.
Honors and Awards:
- Belper Prize, Nottingham University, 1954
- Kellogg Foundation Fellowship, Iowa State University, 1960-61
- Elected Fellow, American Association for the Advancement of Science, 1992
- Elected Fellow, American Academy of Arts and Sciences, 1993
- Wilhelmina Key Invited Lecturer, American Genetic Association, 1993
- Regents' Professor of Ecology and Evolutionary Biology, 1994
- Elected Member, National Academy of Sciences, 1996
Editorial Work:
- American Naturalist
- Journal of Heredity
- Australian Journal of Biological Sciences
- Journal of Medical Entomology
- Bioessays
- Biochemical Genetics
- Biologie Cellulaire
- Journal of Molecular Evolution
- BioScience
- Insect Molecular Biology
- BioEssays
- Molecular Biology and Evolution
- Cancer Research
- Molecular and General Genetics
- Chromosoma
- Molecular Insect Science
- Evolution
- Mutation Research
- Gene
- Nature
- Genetica
- Quarterly Review of Biology
- Genes and Development
- Parasitology Today
- Genetics
- Proc. Natl. Acad. Sci., USA
- Genetical Research
- Science
- Genome
- Theoretical and Applied Genetics
- Heredity
- Trends in Ecology and Evolution
- Hereditas
- Trends in Genetics
- Journal of Experimental Zoology
Associate Editorship: Evolution (1988-91)
Selected Publications:
- Kidwell, M. G., A. W. Nordskog & R. H. Forsythe 1964. Variation among commercial strains of chickens in loss of egg albumen quality. Poultry Sci. 43: 38-42.
- Kidwell, M. G., A. W. Nordskog & R. H. Forsythe 1964. On the problem of correcting albumen quality measures for egg weight. Poultry Sci. 43: 42-49.
- Kidwell, J. F. & M. M. Kidwell 1966. The effects of inbreeding on body weight and abdominal chaeta number in Drosophila melanogaster. Can. J. Genet. Cytol. 8: 207-215.
- Kidwell, J. F. & M. M. Kidwell 1968. Evidence against the mutagenic effects of vibration on Drosophila melanogaster. J. Hered. 59: 231-234.
- Kidwell, J. F., M. L. Tracey, P. Glaser & M. M. Kidwell 1971. A chromosomal analysis of X-ray induced genetic variance of wing length in D. melanogaster. Can. J. Genet. Cytol. 13: 600-606.
- Kidwell, M. G. 1972. Genetic change of recombination value in Drosophila melanogaster: I. Artificial selection for high and low recombination and some properties of recombination-modifying genes. Genetics 70: 419-432.
- Kidwell, M. G. 1972. Genetic change of recombination value in Drosophila melanogaster. II. Simulated natural selection. Genetics 70: 433-443.
- Kidwell, M. G., J. F. Kidwell & M. Nei 1973. A case of high rate of spontaneous mutation affecting viability in Drosophila melanogaster. Genetics 75: 133-153.
- Kidwell M. G. & J. F. Kidwell 1975. Cytoplasm- chromosome interactions in Drosophila melanogaster. Nature 253:755-756.
- Kidwell, M. G. & J. F. Kidwell 1975. Spontaneous male recombination and mutation in isogenic-derived chromosomes of Drosophila melanogaster. J. Hered. 66: 367-375.
- Clegg, M. T., J. F. Kidwell, M. G. Kidwell & N. J. Daniels 1976. Dynamics of correlated genetic systems. I. Selection in the region of the Glued locus of D. melanogaster. Genetics 83: 793-810.
- Kidwell, M. G. & J. F. Kidwell 1976. Selection for male recombination in Drosophila melanogaster. Genetics 84: 333-351.
- Kidwell, M. G., J. F. Kidwell, & P. T. Ives 1977. Spontaneous, non-reciprocal mutation and sterility in strain crosses of Drosophila melanogaster. Mutation Research 42: 89-98.
- Kidwell, M. G., J. F. Kidwell & J. A. Sved 1977. Hybrid dysgenesis in D. melanogaster: a syndrome of aberrant traits including mutation, sterility & male recombination. Genetics 36: 813-33.
- Kidwell, M. G. 1977. Reciprocal differences in female recombination associated with hybrid dysgenesis in Drosophila melanogaster. Genet. Res. 30: 77-88.
- Broadhead, R. S., J. F. Kidwell & M. G. Kidwell 1977. Variation of the recombination fraction in Drosophila melanogaster females. J. Hered. 68: 323-326.
- Clegg, M. T., J. F. Kidwell & M. G. Kidwell 1978. Dynamics of correlated genetic systems. III. Behavior of chromosomal segments under lethal selection. Genetica 48: 95-106.
- Sved, J. A., D. C. Murray, R. E. Schaefer & M. G. Kidwell 1978. Male recombination is not induced in Drosophila melanogaster by extracts of strains with male recombination potential. Nature 257: 457-458.
- Picard, G., J. C. Bregliano, A. Bucheton, J. M. Lavige, A. Pelisson & M. G. Kidwell 1978. Non-Mendelian female sterility and hybrid dysgenesis in Drosophila melanogaster. Genet. Res. 32: 275-287.
- Kidwell, M. G. 1978. Hybrid dysgenesis in Drosophila melanogaster: no suppresser-X effect on male recombination. J. Hered. 64: 417-419.
- Kidwell, M. G. 1979. Hybrid dysgenesis in Drosophila melanogaster: the relationship between the P-M and I-R interaction systems. Genet. Res. 33: 205-217.
- Kidwell M. G. & J. F. Kidwell 1979. Dynamics of natural selection on a lethal fourth chromosome in Drosophila. J. Hered. 70: 123-126.
- Kidwell, M. G. & J. B. Novy 1979. Hybrid dysgenesis in Drosophila melanogaster: sterility resulting from gonadal dysgenesis in the P-M system. Genetics 92: 1127-1140.
- Schaefer, R. E., M. G. Kidwell & A. Fausto-Sterling 1979. Hybrid dysgenesis in Drosophila melanogaster: morphological and cytological studies of ovarian dysgenesis. Genetics 92: 1141-1152.
- Kidwell, M. G., J. B. Novy & S. M. Feeley 1981. Rapid unidirectional change of hybrid dysgenesis potential in Drosophila. J. Hered. 72: 32-38.
- Kidwell, M. G. 1981. The use of pupation height as a method for distinguishing between the sibling species Drosophila melanogaster and Drosophila simulans. Dros. Inf. Serv. 56: 81-82.
- Kidwell, M. G. 1981. Hybrid dysgenesis in Drosophila melanogaster: the genetics of cytotype determination in a neutral strain. Genetics 98: 275-290.
- Rubin, G. M., M. G. Kidwell & P. M. Bingham 1982. The molecular basis of P-M hybrid dysgenesis: The nature of induced mutations. Cell 29: 987-994.
- Bingham, P. M., M. G. Kidwell & G. M. Rubin 1982. The molecular basis of P-M hybrid dysgenesis: The role of the P element, a P strain-specific transposon family. Cell 29: 995-1004.
- Bregliano, J. C. & M. G. Kidwell 1983. Hybrid dysgenesis determinants. In: Mobile Genetic Elements (ed. J. A. Shapiro) pp. 363-410. Academic Press, London, New York.
- Kidwell, M. G. 1983. Intraspecific hybrid sterility. In: The Genetics and Biology of Drosophila, Vol. 3c. (Eds. M. Ashburner, H. Carson, & J. N. Thompson, Jr.) pp. 125-154. Academic Press, London.
- Kidwell, M. G. 1983. Evolution of hybrid dysgenesis determinants in Drosophila melanogaster. Proc. Nat. Acad. Sci. USA 80: 1655-1659.
- Kidwell, M. G. 1983. Hybrid dysgenesis in Drosophila melanogaster : factors affecting chromosomal contamination in the P-M system. Genetics 104: 317-341.
- Kidwell, M. G., T. Frydryk & J. B. Novy 1983. The hybrid dysgenesis potential of Drosophila melanogaster strains of diverse temporal and geographic origin. Dros. Inf. Serv. 59: 63-69.
- Kidwell, M. G. 1984. Hybrid dysgenesis in Drosophila melanogaster : partial sterility associated with embryo lethality in the P-M system. Genet. Res. 44: 11-28.
- Kiyasu, P. K. & M. G. Kidwell 1984. Hybrid dysgenesis in D. melanogaster: the evolution of mixed P and M populations maintained at high temperature. Genet. Res. 44: 251-259.
- Kidwell, M. G. 1984. Hybrid dysgenesis in Drosophila: some implications for genetics evolution and recombinant DNA technology. Bull. Genet. Soc. Canada 15: 53-56.
- Kidwell, M. G. & J. B. Novy 1985. The distribution of hybrid dysgenesis determinants in North American populations of Drosophila melanogaster. Dros. Inf. Serv. 61: 97-100.
- Kidwell, M. G. 1985. Hybrid dysgenesis in Drosophila melanogaster :nature and inheritance of P element regulation. Genetics 111: 337-350.
- Kidwell, M. G. 1986. Molecular and phenotypic aspects of the evolution of hybrid dysgenesis systems. In: Evolutionary Processes and Theory (eds. S. Karlin & E. Nevo) Academic Press, New York, pp. 169-198.
- Kidwell, M. G. & H. M. Sang 1986. Hybrid dysgenesis in Drosophila melanogaster : synthesis of an RP strain by chromosomal contamination. Genet. Res. 47:181-185.
- Kidwell, M. G. 1986. P-M mutagenesis. In: Drosophila: A Practical Approach (ed. D. B. Roberts) I.R.L. Press, Oxford, pp. 59-82.
- Daniels, S. B., S. H. Clark, M. G. Kidwell & A. Chovnick 1987. Genetic transformation of Drosophila melanogaster with an autonomous P element: phenotypic and molecular analyses of long-established transformed lines. Genetics 115: 711-723.
- Boussy, I. A. & M. G. Kidwell 1987. The P-M hybrid dysgenesis cline in eastern Australian Drosophila melanogaster: discrete P, Q and M regions are nearly contiguous. Genetics 115:737-745.
- Black, D. M., Jackson, M. S., Kidwell, M. G. & Dover, G. A. 1987. KP elements repress P-induced hybrid dysgenesis in D. melanogaster. EMBO J. 5: 4125-4135.
- Kidwell, M. G. 1987. A survey of success rates with P element mutagenesis. Drosophila Inform. Serv. 66: 81-86.
- Daniels, S. B., I. A. Boussy, A. Tukey, M. Carrillo & M. G. Kidwell 1988. Variability among true M lines in P-M gonadal dysgenesis potential. Drosophila Inform. Serv. 66: 37-39.
- Kidwell, M. G. 1988. Regulation of expression of P-M hybrid dysgenesis in Drosophila. Banbury Report 30, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY. pp. 183-194.
- Boussy I. A., M. J. Healy, J. G. Oakeshott & M. G. Kidwell 1988. Molecular analysis of the P-M gonadal dysgenesis cline in Eastern Australian Drosophila melanogaster. Genetics 119: 889-902.
- Anxolabéhère, D., M. G. Kidwell & G. Periquet 1988. Molecular characteristics of diverse populations are consistent with the hypothesis of a recent invasion of Drosophila melanogaster by mobile P elements. Mol. Biol. Evol. 5: 252-269.
- Kidwell, M. G., K. Kimura & D. M. Black 1988. Evolution of hybrid dysgenesis potential in Drosophila melanogaster following P element contamination. Genetics 115: 819-828.
- Anxolabéhère, D., M. G. Kidwell & G. Periquet 1989. L'histoire d'une invasion génétique. La Recherche 20: 1328-1338.
- Daniels, S. B., A. Chovnick & M. G. Kidwell 1989. Hybrid dysgenesis in Drosophila simulans lines transformed with autonomous P elements. Genetics 121: 281-291.
- Anxolabéhère, D., M. G. Kidwell & G. Periquet 1990. Historia de una invacion genetica. El Mundo Scientifico 98: 48-58.
- Kidwell, M. G. 1990. Evolutionary aspects of hybrid dysgenesis in Drosophila. (Proc. of a Symposium on Hybridization and Introgression in Insects. XVIII International Congress of Entomology. Editors J. Spence & R. Gooding). Can. J. Zool. 68: 1716-1726.
- Kidwell, M. G., K. R. Peterson, S. B. Daniels 1990. Evolution of P elements in the genus Drosophila. pp. 107-116, in: Molecular Evolution, UCLA Symposium on Molecular and Cellular Biology, New Series, Vol. 122. Eds M. Clegg & S. O'Brien. Alan R. Liss, Inc. New York, NY.
- Daniels, S. B., K. R. Peterson, L. D. Strausbaugh, M. G. Kidwell & A. Chovnick 1990. Evidence for horizontal transmission of the P transposable element between Drosophila species. Genetics 124: 339-355.
- Kidwell, M. G. & K. R. Peterson 1991. Evolution of transposable elements in Drosophila, pp. 139-154, In: Proceedings of 1989 Wistar Symposium on New Perspectives in Evolution. Editors L. Warren & M. Messelson. Alan R. Liss, Inc. New York, NY.
- Houck, M. A., J. B. Clark, K. R. Peterson & M. G. Kidwell 1991. Possible horizontal transfer of Drosophila genes by the mite Proctolaelaps regalis. Science 253: 1125-1129.
- de Frutos, R., K. R. Peterson & M. G. Kidwell. 1992. Distribution of Drosophila melanogaster transposable element sequences in species of the obscura group. Chromosoma 101: 293-300.
- Kidwell, M. G. 1992. Horizontal transfer of the P element and other short inverted repeat transposons. Genetica 19: 913-916.
- Kidwell, M. G. & J. M. C. Ribeiro 1992. Can transposable elements be used to drive disease refractoriness genes into vector populations? Parasitology Today 86: 275-286.
- Kidwell, M. G. 1992. Horizontal transfer. Curr. Opinion. Genet. Develop. 2: 868-873.
- Kidwell, M. G.. 1993. The voyage of an ancient mariner. Nature 362:202.
- Kimura, K., Okumura T., Ninaki O., Kidwell, M. G. & Suzuki, K. 1993. Transposable elements in commercially useful insects: I. Southern hybridization study of silkworms and honeybees using Drosophila probes. Japan J. Genet. 68:63-71.
- Kidwell, M. G. 1993. Lateral transfer in natural populations of eukaryotes. Ann. Rev. Genet. 27: 235-256.
- Ribeiro, J. M. C. & M. G. Kidwell 1994. Transposable elements as population drive mechanisms: specification of critical parameter values. J. Med. Entomology 31: 10-16.
- Clark, J. B., W. P. Maddison & M. G. Kidwell 1994. Phylogenetic analysis supports horizontal transfer of P transposable elements. Mol. Biol. Evol. 11:40-50.
- Kidwell, M. G. 1994. The evolutionary history of the P family of transposable elements. J. Heredity 85: 339-346.
- Kimura, K. & M. G. Kidwell 1994. Differences in P element population dynamics between the sibling species Drosophila melanogaster and Drosophila simulans. Genet. Res. 63: 27-38.
- Kim, W. & Kidwell, M. G. 1994. In situ hybridization to polytene chromosomes using Digoxigenin-11-dUTP labeled probes. Drosophila Information Service 75:44-47.
- Kim, W., M. Wojciechowski, L. Bieling & M. G. Kidwell 1994. Genetic transformation with P transposable vectors carrying the rosy gene in D. melanogaster. Drosophila Information Service 75:169-171
- Ribeiro, J. M. C. & M. G. Kidwell 1994. Response to letter to the Editor. J. Med. Entomology 31: 10-16.
- Clark, J. B. & M. G. Kidwell 1995. Molecular biology and evolution of P transposable elements in Drosophila. Evolucion Biologica 8/9: 1-36.
- Clark, J. B., T. K. Altheide, M. J. Schlosser & M. G. Kidwell. 1995. Molecular evolution of P transposable elements in the genus Drosophila. I. The saltans and willistoni species groups. Mol. Biol. Evol. 12:902-913.
- Prokchorova, A. V., C. M. A. Carareto, M. F. Wojciechowski and M. G. Kidwell. 1995. A new autonomous P element vector with a multiple cloning site for insertion of a variety of DNA sequences. Drosophila Information Service 76:191-192.
- Kidwell, M. G. and D. Lisch. 1997. Transposable elements as sources of variation in animals and plants. Proc. Natl. Acad. Sci. 94: 7704-7711.
- Clark, J. B. and M. G. Kidwell 1997. A phylogenetic perspective on P element evolution in Drosophila. Proc. Natl. Acad. Sci. USA 94: 11428-11433.
- Clark, J. B. and M. G. Kidwell 1997. Evidence for horizontal transfer of the P transposable element between Drosophila species. Proc. Conf. on Horizontal Transfer, Fallen Leaf Lake, CA. Sept. 1997.
- Carareto, C. M. A., W. Kim, M. F. Wojciechowski, P. M. O'Grady, A. V. Prokchorova, J. C. Silva and M. G. Kidwell. 1997. Testing transposable elements as genetic drive mechanisms using Drosophila P element constructs as a model system. Genetica 101: 13-34.
- O’Grady, P. M., J. B. Clark and M. G. Kidwell. 1998. Phylogeny of the Drosophila saltans species group based on combined analysis of nuclear and mitochondrial DNA sequences. Mol. Biol. and Evol. 15: 656-664.
- Clark, J. B., P. Kim and M. G. Kidwell. 1998. Molecular evolution of P transposable elements in the genus Drosophila. III. The melanogaster species group. Mol. Biol. Evol. 15: 746-755.
- Kidwell, M. G. and A. R. Wattam 1998. Commentary. An important step forward in the manipulation of mosquito disease vectors. Proc. Natl. Acad. Sci. 95:3349-3450.
- Kidwell, M. G. and D. R. Lisch. 1998. Transposons unbound. Nature 393: 22-23.
- García-Plannells, J., Paricio, N., de Frutos, R., Clark, J. B., Kidwell, M. G. 1998. Molecular evolution of P transposable elements in the genus Drosophila. II. The obscura species group. J. Mol. Evol. 47: 282-91.
- Lee, S. H., J. B. Clark, and M. G. Kidwell. 1999. A P-homologous sequence in the house fly, Musca domestica. Insect Molecular Biology 8:491-500.
- Zelentsova, H., H. Poluectova, L. Mnjoian, G. Lyozin, V. Veleikodvorskaja, L. Zhivotovski, M. G. Kidwell and M. B. Evgen'ev 1999. Distribution and evolution of mobile elements in the virilis species group of Drosophila. Chromosoma 108: 443-456.
- Kidwell, M. G. and D. R. Lisch 2000. Transposable elements and host genome evolution. Trends Ecol. Evol. 15: 95-99.
- Kidwell, M. G. and D. R. Lisch 2000. Reply to Transposable elements and asexual reproduction Trends Ecol. Evol. 15: 288.
- Kidwell, M. G. and M. B. Evgen'ev. 2000. How valuable are model organisms for transposable element studies? Genetica 107:103-111
- Evgen'ev, M. B., H. Zelentsova, L. Mnjoian, H. Poluectova and M. G. Kidwell 2000. Invasion of Drosophila virilis by the Penelope transposable element. Chromosoma 109:350-357.
- Silva, J. C. and Kidwell, M. G. 2000. Selection and horizontal transfer in the evolution of P elements. . Mol. Biol. Evol. 17:1542-1557
- Evgen'ev, M. B., Zelentsova, H., Poluectova, H., Lyozin, G. T., Veleikodvorskaja, V., Pyatkov, K. I., Zhivotovsky, L. A. and Kidwell, M. G. 2000. Mobile elements and chromosomal evolution in the virilis group of Drosophila. Proc. Natl. Acad. Sci. USA 97:11337-11342..
- Kidwell, M. G. 2001. Hybrid dysgenesis determinants and other useful transposable elements in Drosophila. Encyclopedia of Genetics. Ed. E. C. R. Reeve. Dearborn Publishers, New York.
- Kidwell, M. G. and D. R. Lisch (2001) Perspective: Transposable elements, parasitic DNA and genome evolution. Evolution 55.1-24..
- Kidwell, M. G. 2001. Horizontal transfer. In: Encyclopedia of Genetics, Eds. Sydney Brenner and Jeffrey Miller. Academic Press, London..
- Kidwell, M. G. 2001. Hybrid dysgenesis In: Encyclopedia of Genetics, Eds. Sydney Brenner and Jeffrey Miller Academic Press, London..
- Lyozin, G. T., K. S. Makarova, V. V. Velikodvorskaja, H. S. Zelentsova, R. R. Khechumian, M. G. Kidwell, E. V. Koonin, and M. B. Evgen'ev. 2001. The structure and evolution of Penelope in the Drosophila virilis species group: an ancient lineage of retroelements. J. Mol. Evol. 52: 445-456.
- Loreto, E. L. da S., Valente, V. L. da S., A. Zaha , J. C. Silva, and Kidwell, M.G. 2001. Drosophila mediopunctata P transposable element: a new example of horizontal transfer (J. Heredity 95: 3721-381.
- Lezin, G. T., K. V. Makarova, V. V. Velikodvorskaia, E. S. Zelentsova, R. R. Kechumian, M. G. Kidwell, E. V. Kunin and M. B. Evgen'ev 2001. Structure and evolutionary role of the Penelope mobile element in Drosophila species of the virilis group. Mol Biol (Mosk) 35:805-815.
- Kidwell, M. G. and A. J. Holyoake 2001. Transposon-induced hotspots for genomic instability. Genome Res. 11: 1321-1322.
- Kidwell, M. G. and D. R. Lisch 2001. Transposable Elements as Sources of Genomic Variation. In: Mobile DNA II. American Society of Microbiology Press, pps 59-92.
- Clark, J. B, Silva, J. C. and M. G. Kidwell . 2002. Evidence for horizontal transfer of the P transposable element. In Horizontal transfer (2nd edition) M. Synanen and C. Kado eds. Academic Press, London.. .
- O'Grady, P. M. and M. G. Kidwell 2002. Phylogeny of the subgenus Sophophora (Diptera: Drosophilidae) based on combined analysis of nuclear and mitochondrial sequences. Mol Phylogenet Evol. 22: 442-453.
- Kidwell, M. G. 2002. Book Review: Keeping pace with opportunistic DNA. Science 195: 2219-2220.
- Kidwell, M. G. 2002. Transposable elements and the evolution of genome size in eukaryotes. Genetica 115: 49-63.
- Holyoake, A. J. and M. G. Kidwell, 2003. Vege and Mar: two novel hAT MITE families from Drosophila willistoni. Mol. Biol. Evol..20: 163-167.